ER stress signaling by regulated splicing: IRE1/HAC1/XBP1
Back SH;Schröder M;Lee K;Zhang K;Kaufman RJ;;
Methods (San Diego, Calif.)2005Vol. 35pp. -
340
sh2005methodser
Abstract
The endoplasmic reticulum (ER) serves many specialized functions in the cell including calcium storage and gated release, biosynthesis of membrane and secretory proteins, and production of lipids and sterols. Therefore, the ER integrates many internal and external signals to coordinate downstream re …