SIRT1 controls endothelial angiogenic functions during vascular growth
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SIRT1 controls endothelial angiogenic functions during vascular growth

Michael Potente, Laleh Ghaeni, Danila Baldessari, Raul Mostoslavsky, Lothar Rossig, Franck Dequiedt, Judith Haendeler, Marina Mione, Elisabetta Dejana, Frederick W. Alt, Andreas M. Zeiher, Stefanie Dimmeler;Michael Potente;Laleh Ghaeni;Danila Baldessari;Raul Mostoslavsky;Lothar Rossig;Franck Dequiedt;Judith Haendeler;Marina Mione;Elisabetta Dejana;Frederick W. Alt;Andreas M. Zeiher;Stefanie Dimmeler;
genes & development 2007 Vol. 21 pp. 2644-
88
dimmeler2007genessirt1

Abstract

The nicotinamide adenine dinucleotide (NAD[+] )-dependent histone deacetylase Sir2 regulates life-span in various species. Mammalian homologs of Sir2 are called sirtuins (SIRT1–SIRT7). In an effort to define the role of sirtuins in vascular homeostasis, ...

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DOI:
10.1101/gad.435107
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC200032...

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