Establishment of left-right asymmetry in vertebrate development: the node in mouse embryos
Abstract
Establishment of vertebrate left-right asymmetry is a critical process for normal embryonic development. After the discovery of genes expressed asymmetrically along the left-right axis in chick embryos in the mid 1990s, the molecular mechanisms responsible for left-right patterning in vertebrate emb …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
gene expression regulation
animals
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
N.I.H.
Extramural
mutation
biological
developmental
signal transduction
mice / genetics
bone morphogenetic proteins / genetics
pmid:23771646
pmc3914763
doi:10.1007/s00018-013-1399-9
yoshihiro komatsu
yuji mishina
body patterning / genetics
body patterning / physiology*
bone morphogenetic proteins / physiology
cilia / genetics
cilia / physiology
mice / embryology*
nodal protein / genetics
nodal protein / physiology
organizers
embryonic / embryology*
embryonic / physiology*
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269687
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