Wnt/β-catenin signalling in prostate cancer
Abstract
The Wnts are secreted cysteine-rich glycoproteins that have important roles in the developing embryo as well as in tissue homeostasis in adults. Dysregulation of Wnt signalling can lead to several types of cancer, including prostate cancer. A hallmark of the signalling pathway is the stabilization o …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
Receptors
cell differentiation
cell proliferation
wnt signaling pathway*
androgen / metabolism
epithelial-mesenchymal transition
prostatic neoplasms / metabolism*
robert m kypta
pmid:22710668
doi:10.1038/nrurol.2012.116
jonathan waxman
adenocarcinoma / metabolism*
lymphoid enhancer-binding factor 1 / metabolism
t cell transcription factor 1 / metabolism
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269647
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