Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion

Advanced Glycation End Product 3 (AGE3) Suppresses the Mineralization of Mouse Stromal ST2 Cells and Human Mesenchymal Stem Cells by Increasing TGF-β Expression and Secretion

Notsu, Masakazu;Yamaguchi, Toru;Okazaki, Kyoko;Tanaka, Ken-ichiro;Ogawa, Noriko;Kanazawa, Ippei;Sugimoto, Toshitsugu;
endocrinology 2014 Vol. 155 pp. 2402-2410
130
masakazu2014endocrinologyadvanced

Abstract

In diabetic patients, advanced glycation end products (AGEs) cause bone fragility because of deterioration of bone quality. We previously showed that AGEs suppr

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