Establishment and Characterization of Immortalized Miniature Pig Pancreatic Cell Lines Expressing Oncogenic K-Ras G12D
Abstract
In recent decades, many studies on the treatment and prevention of pancreatic cancer have been conducted. However, pancreatic cancer remains incurable, with a high mortality rate. Although mouse models have been widely used for preclinical pancreatic cancer research, these models have many differenc …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
gene expression regulation
animals
pubmed abstract
nih
national institutes of health
national library of medicine
Disease Models
Animal
cell line
pancreatic neoplasms / pathology
sun-uk kim
swine
signal transduction / genetics
cell transformation
miniature
neoplastic / genetics
pmid:33233448
pmc7700231
doi:10.3390/ijms21228820
hae-jun yang
bong-seok song
pancreas / metabolism*
pancreas / pathology
pancreatic ducts / metabolism
pancreatic ducts / pathology
pancreatic neoplasms / genetics*
precancerous conditions / genetics*
precancerous conditions / metabolism
precancerous conditions / pathology
proto-oncogene proteins p21(ras) / genetics*
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269566
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