The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective

The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective

de Beaurepaire R;Sinclair JMA;Heydtmann M;Addolorato G;Aubin HJ;Beraha EM;Caputo F;Chick JD;de La Selle P;Franchitto N;Garbutt JC;Haber PS;Jaury P;Lingford-Hughes AR;Morley KC;Müller CA;Owens L;Pastor A;Paterson LM;Pélissier F;Rolland B;Stafford A;Thompson A;van den Brink W;Leggio L;Agabio R;;
Frontiers in psychiatry 2019 Vol. 9 pp. -
159
r2019frontiersthe

Abstract

Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of this drug remains controversial, in part due to uncertainty r …

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