The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans

Maria C. Ow, Natalia J. Martinez, Philip H. Olsen, Howard S. Silverman, M. Inmaculada Barrasa, Barbara Conradt, Albertha J.M. Walhout, Victor Ambros;Maria C. Ow;Natalia J. Martinez;Philip H. Olsen;Howard S. Silverman;M. Inmaculada Barrasa;Barbara Conradt;Albertha J.M. Walhout;Victor Ambros;
genes & development 2008 Vol. 22 pp. 2520-
100
ambros2008genesthe

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally via antisense base-pairing. Although miRNAs are involved in a variety of important biological functions, little is known about their transcriptional regulation. ...

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