Central Sirt1 Regulates Body Weight and Energy Expenditure Along With the POMC-Derived Peptide α-MSH and the Processing Enzyme CPE Production in Diet-Induced Obese Male Rats
Cyr, Nicole E.;Steger, Jennifer S.;Toorie, Anika M.;Yang, Jonathan Z.;Stuart, Ronald;Nillni, Eduardo A.;
endocrinology2014Vol. 155pp. 2423-2435
196
e.2014endocrinologycentral
Abstract
In the periphery, the nutrient-sensing enzyme Sirtuin 1 (silent mating type information regulation 2 homolog 1 [Sirt1]) reduces body weight in diet-induced obes