Vasodilating mechanisms of levosimendan: involvement of K+ channels
Abstract
Levosimendan, a novel agent developed for the treatment of acute and decompensated heart failure, exerts potent positive inotropic action and peripheral vasodilatory effects. The mechanism of vasodilation by levosimendan may involve reduction of Ca2+ sensitivity of contractile proteins in vascular s …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
simendan
hydrazones / pharmacology*
pyridazines / pharmacology*
pmid:17452812
doi:10.1254/jphs.cp0060010
oguzhan yildiz
blood vessels / drug effects
blood vessels / physiology
potassium channels / physiology*
vasodilation / drug effects*
vasodilation / physiology
vasodilator agents / pharmacology
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