Noggin is a mesenchymally derived stimulator of hair-follicle induction

Noggin is a mesenchymally derived stimulator of hair-follicle induction

Botchkarev VA;Botchkareva NV;Roth W;Nakamura M;Chen LH;Herzog W;Lindner G;McMahon JA;Peters C;Lauster R;McMahon AP;Paus R;;
Nature Cell Biology 1999 Vol. 1 pp. -
272
va1999naturenoggin

Abstract

The induction of developmental structures derived from the ectoderm, such as the neural tube or tooth, occurs through neutralization of the inhibitory activity of members of the bone-morphogenetic protein (BMP) family by BMP antagonists. Here we show that, during hair-follicle development, the neura …

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