Secreted antagonists of the Wnt signalling pathway
Abstract
The extracellular antagonists of the Wnt signalling pathway can be divided into two broad classes. Both classes of molecule prevent ligand-receptor interactions, but by different mechanisms: members of the first class, which include the sFRP (secreted Frizzled-related protein) family, WIF (Wnt inhib …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
gene expression regulation
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
proteins / metabolism
signal transduction / physiology*
adaptor proteins
signal transducing
repressor proteins / metabolism
Yoshiaki Kawano
Robert Kypta
wnt proteins
intercellular signaling peptides and proteins / metabolism
proto-oncogene proteins / metabolism*
carrier proteins / metabolism
membrane proteins / metabolism
pmid:12775774
doi:10.1242/jcs.00623
developmental / genetics
xenopus proteins
zebrafish proteins*
Citation
ID:
269036
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