Telomere Length Recovery a Strong Predictor of Overall Survival In Acute Promyelocytic Leukemia

Telomere Length Recovery a Strong Predictor of Overall Survival In Acute Promyelocytic Leukemia

Muhamed Baljevic, Bogdan Dumitriu, Ju-Whei Lee, Elisabeth M. Paietta, Peter H. Wiernik, Janis Racevskis, Christina Chen, Eytan M. Stein, Robert E. Gallagher, Jacob M. Rowe, Frederick R. Appelbaum, Bayard L. Powell, Richard A. Larson, Steven E. Coutré, Jeffrey Lancet, Mark R. Litzow, Selina M. Luger, Neal S. Young, Martin S. Tallman;Muhamed Baljevic;Bogdan Dumitriu;Ju-Whei Lee;Elisabeth M. Paietta;Peter H. Wiernik;Janis Racevskis;Christina Chen;Eytan M. Stein;Robert E. Gallagher;Jacob M. Rowe;Frederick R. Appelbaum;Bayard L. Powell;Richard A. Larson;Steven E. Coutré;Jeffrey Lancet;Mark R. Litzow;Selina M. Luger;Neal S. Young;Martin S. Tallman;
acta haematologica 2016 Vol. 136 pp. 210-
158
tallman2016actatelomere

Abstract

Telomeres are the capping ends of chromosomes that protect the loss of genetic material and prevent chromosomal instability. In human tissue-specific stem/progenitor cells, telomere length is maintained by the telomerase complex, which consists of a reverse ...

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