National Center for Biotechnology Information NCBI NLM MEDLINE Mice gene expression regulation animals humans pubmed abstract nih national institutes of health national library of medicine models research support u.s. gov't non-p.h.s. male N.I.H. Extramural neoplastic* Receptors ligands Knockout biological disease progression signal transduction scid receptor transforming growth factor beta / metabolism* transforming growth factor beta / metabolism wnt proteins / metabolism* prostatic neoplasms / metabolism* protein-serine-threonine kinases / metabolism neoplasm transplantation pmid:18724388 pmc3222150 doi:10.1038/onc.2008.293 x li v placencio n a bhowmick adenocarcinoma / metabolism paracrine communication transforming growth factor-beta type ii wnt3 protein wnt3a protein