Wnt/beta-catenin signaling in development and disease

Wnt/beta-catenin signaling in development and disease

Clevers H;;
Cell 2006 Vol. 127 pp. -
234
h2006cellwnt/beta-catenin

Abstract

A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal transduction cascade over the last two decades. Wnt genes encode small secreted proteins that are found in all animal genomes. Wnt signaling is involved in virtually every aspect of embryonic development and also …

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