Wnt/beta-catenin signaling in development and disease
Clevers H;;
Cell2006Vol. 127pp. -
234
h2006cellwnt/beta-catenin
Abstract
A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal transduction cascade over the last two decades. Wnt genes encode small secreted proteins that are found in all animal genomes. Wnt signaling is involved in virtually every aspect of embryonic development and also …