Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis

Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis

Zhang Y;Zhang J;Lin Y;Lan Y;Lin C;Xuan JW;Shen MM;McKeehan WL;Greenberg NM;Wang F;;
development (cambridge, england) 2008 Vol. 135 pp. -
489
y2008developmentrole

Abstract

The fibroblast growth factor (FGF) regulates a broad spectrum of biological activities by activation of transmembrane FGF receptor (FGFR) tyrosine kinases and their coupled intracellular signaling pathways. FGF receptor substrate 2alpha (FRS2alpha) is an FGFR interactive adaptor protein that links m …

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