CpG islands and the regulation of transcription

CpG islands and the regulation of transcription

Aimée M. Deaton, Adrian Bird;Aimée M. Deaton;Adrian Bird;
genes & development 2011 Vol. 25 pp. 1010-
128
bird2011genescpg

Abstract

Vertebrate CpG islands (CGIs) are short interspersed DNA sequences that deviate significantly from the average genomic pattern by being GC-rich, CpG-rich, and predominantly nonmethylated. Most, perhaps all, CGIs are sites of transcription initiation, ...

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