Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway
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Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway

Dasa Longman, Ronald H.A. Plasterk, Iain L. Johnstone, Javier F. Cáceres;Dasa Longman;Ronald H.A. Plasterk;Iain L. Johnstone;Javier F. Cáceres;
genes & development 2007 Vol. 21 pp. 1075-
114
cáceres2007genesmechanistic

Abstract

The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons (PTCs). Seven genes (smg-1–7, for suppressor with morphological effect on genitalia) that are essential for NMD were originally identified ...

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DOI:
10.1101/gad.417707
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC185523...

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