Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration
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Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration

Ryan D. Mohan, George Dialynas, Vikki M. Weake, Jianqi Liu, Skylar Martin-Brown, Laurence Florens, Michael P. Washburn, Jerry L. Workman, Susan M. Abmayr;Ryan D. Mohan;George Dialynas;Vikki M. Weake;Jianqi Liu;Skylar Martin-Brown;Laurence Florens;Michael P. Washburn;Jerry L. Workman;Susan M. Abmayr;
genes & development 2014 Vol. 28 pp. 259-
131
abmayr2014genesloss

Abstract

The Spt–Ada–Gcn5–acetyltransferase (SAGA) chromatin-modifying complex possesses acetyltransferase and deubiquitinase activities. Within this modular complex, Ataxin-7 anchors the deubiquitinase activity to the larger complex. Here ...

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DOI:
10.1101/gad.225151.113
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC392396...

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