Ability of baclofen in reducing alcohol intake and withdrawal severity: I--Preclinical evidence
Abstract
These results are in close agreement with those of a preliminary clinical study and suggest that baclofen may constitute a novel therapeutic agent for alcoholism.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
Rats
dose-response relationship
drug
wistar
drug evaluation
ethanol / adverse effects*
motivation
alcohol drinking / prevention & control*
preclinical
alcohol drinking / psychology
alcoholism / psychology
substance withdrawal syndrome / prevention & control*
substance withdrawal syndrome / psychology
pmid:10656194
g colombo
r agabio
g l gessa
baclofen / pharmacology*
gaba agonists / pharmacology*
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268165
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