Hydroxychloroquine as Pre-exposure Prophylaxis for Coronavirus Disease 2019 (COVID-19) in Healthcare Workers: A Randomized Trial

Hydroxychloroquine as Pre-exposure Prophylaxis for Coronavirus Disease 2019 (COVID-19) in Healthcare Workers: A Randomized Trial

Rajasingham, Radha;Bangdiwala, Ananta S;Nicol, Melanie R;Skipper, Caleb P;Pastick, Katelyn A;Axelrod, Margaret L;Pullen, Matthew F;Nascene, Alanna A;Williams, Darlisha A;Engen, Nicole W;Okafor, Elizabeth C;Rini, Brian I;Mayer, Ingrid A;McDonald, Emily G;Lee, Todd C;Li, Peter;MacKenzie, Lauren J;Balko, Justin M;Dunlop, Stephen J;Hullsiek, Katherine H;Boulware, David R;Lofgren, Sarah M;COVID PREP team;Abassi, Mahsa;Balster, Andrew;Collins, Lindsey B;Drobot, Glen;Krakower, Douglas S;Lother, Sylvain A;MacKay, Dylan S;Meyer-Mueller, Cameron;Selinsky, Stephen;Solvason , Dayna;Zarychanski, Ryan;Zash, Rebecca;
clinical infectious diseases 2021 Vol. 72 pp. e835-e843
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radha2021clinicalhydroxychloroquine

Abstract

In this randomized clinical trial of 1483 high-risk healthcare workers, there was no significant reduction in incidence of COVID-19 with once-weekly or twice-we

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