Comprehensive Molecular Profiles of Functionally Effective MSC-Derived Extracellular Vesicles in Immunomodulation

Comprehensive Molecular Profiles of Functionally Effective MSC-Derived Extracellular Vesicles in Immunomodulation

Kim H;Lee MJ;Bae EH;Ryu JS;Kaur G;Kim HJ;Kim JY;Barreda H;Jung SY;Choi JM;Shigemoto-Kuroda T;Oh JY;Lee RH;;
molecular therapy : the journal of the american society of gene therapy 2020 Vol. 28 pp. -
316
h2020molecularcomprehensive

Abstract

Accumulating evidence indicates that mesenchymal stem/stromal cell-derived extracellular vesicles (MSC-EVs) exhibit immunomodulatory effects by delivering therapeutic RNAs and proteins; however, the molecular mechanism underlying the EV-mediated immunomodulation is not fully understood. In this stud …

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