Multipotent and unipotent progenitors contribute to prostate postnatal development

Multipotent and unipotent progenitors contribute to prostate postnatal development

Ousset M;Van Keymeulen A;Bouvencourt G;Sharma N;Achouri Y;Simons BD;Blanpain C;;
Nature Cell Biology 2012 Vol. 14 pp. -
316
m2012naturemultipotent

Abstract

The prostate is a glandular epithelium composed of basal, luminal and neuroendocrine cells that originate from the urogenital sinus during embryonic development. After birth, the prostate keeps developing until the end of puberty. Here, we used inducible genetic lineage tracing experiments in mice t …

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