Antiandrogen Flutamide Protects Male Mice From Androgen-Dependent Toxicity in Three Models of Spinal Bulbar Muscular Atrophy
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Antiandrogen Flutamide Protects Male Mice From Androgen-Dependent Toxicity in Three Models of Spinal Bulbar Muscular Atrophy

Renier, Kayla J.;Troxell-Smith, Sandra M.;Johansen, Jamie A.;Katsuno, Masahisa;Adachi, Hiroaki;Sobue, Gen;Chua, Jason P.;Sun Kim, Hong;Lieberman, Andrew P.;Breedlove, S. Marc;Jordan, Cynthia L.;
endocrinology 2014 Vol. 155 pp. 2624-2634
145
j.2014endocrinologyantiandrogen

Abstract

Spinal and bulbar muscular atrophy (SBMA) is a late-onset, progressive neurodegenerative disease linked to a polyglutamine (polyQ) expansion in the androgen rec

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