Class IA Phosphatidylinositol 3-Kinase Inhibition Inhibits Cell Growth and Proliferation in Mantle Cell Lymphoma
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Class IA Phosphatidylinositol 3-Kinase Inhibition Inhibits Cell Growth and Proliferation in Mantle Cell Lymphoma

Yoko Tabe, Linhua Jin, Marina Konopleva, Masato Shikami, Shinya Kimura, Michael Andreeff, Mark Raffeld, Takashi Miida;Yoko Tabe;Linhua Jin;Marina Konopleva;Masato Shikami;Shinya Kimura;Michael Andreeff;Mark Raffeld;Takashi Miida;
acta haematologica 2014 Vol. 131 pp. 59-
141
miida2014actaclass

Abstract

Constitutive activation of the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin signaling pathway preferentially occurs in aggressive blastoid variants of mantle cell lymphoma (MCL) and is implicated in the pathogenesis of this disease. ...

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DOI:
10.1159/000353164
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC77113...

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