Senescence of human fibroblasts induced by oncogenic Raf
Jiyue Zhu, Douglas Woods, Martin McMahon, J. Michael Bishop;Jiyue Zhu;Douglas Woods;Martin McMahon;J. Michael Bishop;
genes & development1998Vol. 12pp. 2997-
81
bishop1998genessenescence
Abstract
The oncogenes RAS and RAF came to view as agents of neoplastic transformation. However, in normal cells, these genes can have effects that run counter to oncogenic transformation, such as arrest of the cell division cycle, induction of cell differentiation, ...