Astrocytes respond to a neurotoxic Aβ fragment with state-dependent Ca2+ alteration and multiphasic transmitter release

Astrocytes respond to a neurotoxic Aβ fragment with state-dependent Ca2+ alteration and multiphasic transmitter release

Cuong Pham, Karine Hérault, Martin Oheim, Steeve Maldera, Vincent Vialou, Bruno Cauli, Dongdong Li;Cuong Pham;Karine Hérault;Martin Oheim;Steeve Maldera;Vincent Vialou;Bruno Cauli;Dongdong Li;
acta neuropathologica communications 2021 Vol. 9 pp. -
146
li2021actaastrocytes

Abstract

Excessive amounts of amyloid β (Aβ) peptide have been suggested to dysregulate synaptic transmission in Alzheimer’s disease (AD). As a major type of glial cell in the mammalian brain, astrocytes regulate neuronal function and undergo ...

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