Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice
Abstract
Lymphoid enhancer factor 1 (LEF-1) is a sequence-specific DNA-binding protein that is expressed in pre-B and T lymphocytes of adult mice, and in the neural crest, mesencephalon, tooth germs, whisker follicles, and other sites during embryogenesis. We have generated mice carrying a homozygous germ-li …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
non-p.h.s.
Genes
dna-binding proteins / genetics
transcription factors / genetics
mammary glands
Embryonic and Fetal Development*
mutant strains
pmid:7958926
doi:10.1101/gad.8.22.2691
c van genderen
r m okamura
r grosschedl
dna-binding proteins / analysis*
embryonic induction
epithelium / embryology*
lethal
germ-line mutation
hair / embryology
lymphoid enhancer-binding factor 1
animal / embryology
mesoderm / physiology*
neural crest / embryology
tooth / embryology
transcription factors / analysis*
trigeminal nerve / embryology
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267668
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