Phosphorylation and activation of 13S condensin by Cdc2 in vitro
Kimura K;Hirano M;Kobayashi R;Hirano T;;
Science (New York, N.Y.)1998Vol. 282pp. -
328
k1998sciencephosphorylation
Abstract
13S condensin is a multisubunit protein complex essential for mitotic chromosome condensation in Xenopus egg extracts. Purified 13S condensin introduces positive supercoils into DNA in the presence of topoisomerase I and adenosine triphosphate in vitro. The supercoiling activity of 13Scondensin was …