Group G Streptococcus Induces an Autoimmune Carditis Mediated by Interleukin 17A and Interferon γ in the Lewis Rat Model of Rheumatic Heart Disease
Sikder, Suchandan;Williams, Natasha L;Sorenson, Alanna E;Alim, Md A;Vidgen, Miranda E;Moreland, Nicole J;Rush, Catherine M;Simpson, Robert S;Govan, Brenda L;Norton, Robert E;Cunningham, Madeleine W;McMillan, David J;Sriprakash, Kadaba S;Ketheesan, Natkunam;
The Journal of infectious diseases2018Vol. 218pp. 324-335
88
suchandan2018thegroup
Abstract
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune sequelae of group A streptococcal infections. Here we provide experimental evidence