A phosphorylation-acetylation switch regulates STAT1 signaling
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A phosphorylation-acetylation switch regulates STAT1 signaling

Oliver H. Krämer, Shirley K. Knauer, Georg Greiner, Enrico Jandt, Sigrid Reichardt, Karl-Heinz Gührs, Roland H. Stauber, Frank D. Böhmer, Thorsten Heinzel;Oliver H. Krämer;Shirley K. Knauer;Georg Greiner;Enrico Jandt;Sigrid Reichardt;Karl-Heinz Gührs;Roland H. Stauber;Frank D. Böhmer;Thorsten Heinzel;
genes & development 2009 Vol. 23 pp. 223-
92
heinzel2009genesa

Abstract

Cytokines such as interferons (IFNs) activate signal transducers and activators of transcription (STATs) via phosphorylation. Histone deacetylases (HDACs) and the histone acetyltransferase (HAT) CBP dynamically regulate STAT1 acetylation. Here we show ...

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DOI:
10.1101/gad.479209
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC264853...

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