The selectivity of protein kinase inhibitors: a further update
Abstract
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases. On the basis of this information, the effects of compounds that we have studied in cells and other data in the literature, we recommend the …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
amino acid sequence
cell line
phosphorylation
drug design
pmid:17850214
pmc2267365
doi:10.1042/bj20070797
jenny bain
lorna plater
philip cohen
enzyme activation
mitogen-activated protein kinases / antagonists & inhibitors*
mitogen-activated protein kinases / metabolism
protein kinase inhibitors / pharmacology*
recombinant proteins / antagonists & inhibitors
spodoptera
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267548
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