Intrapartum antibiotic prophylaxis for the prevention of perinatal group B streptococcal disease: experience in the United States and implications for a potential group B streptococcal vaccine
Abstract
Group B Streptococcus (GBS) emerged as the leading cause of newborn infection in the United States in the 1970s. In the 1980s clinical trials demonstrated that giving intrapartum intravenous ampicillin or penicillin to mothers at risk was highly effective at preventing invasive GBS disease in the fi …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
humans
pubmed abstract
nih
national institutes of health
national library of medicine
pregnancy
research support
u.s. gov't
female
Infant
newborn
P.H.S.
United States
anti-bacterial agents / therapeutic use
penicillins / therapeutic use
streptococcal infections / microbiology
premature birth
infectious disease transmission
streptococcal infections / drug therapy*
antibiotic prophylaxis / methods*
jennifer r verani
diseases / prevention & control
vertical / prevention & control*
pmid:23219695
doi:10.1016/j.vaccine.2012.11.056
stephanie j schrag
ampicillin / therapeutic use
diseases / drug therapy*
diseases / microbiology
prenatal diagnosis
reproductive tract infections / drug therapy*
reproductive tract infections / microbiology
streptococcal infections / prevention & control
streptococcal vaccines
streptococcus agalactiae / immunology
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267475
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