Histoplasma capsulatum utilizes siderophores for intracellular iron acquisition in macrophages
Abstract
Histoplasma capsulatum is a dimorphic fungal pathogen that survives and replicates within macrophages (MΦ). Studies in human and murine MΦ demonstrate that the intracellular growth of H. capsulatum yeasts is exquisitely sensitive to the availability of iron. As H. capsulatum produces hydroxamate sid …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Inbred C57BL
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
male
N.I.H.
Extramural
Disease Models
Animal
Cells
Cultured
lung diseases / pathology
Survival Analysis
microbial
lung / microbiology
macrophages / microbiology*
iron / metabolism*
colony count
gene knockout techniques
pmid:21341981
doi:10.3109/13693786.2011.558930
jeremy hilty
a george smulian
simon l newman
gene knockdown techniques
histoplasma / metabolism*
histoplasma / pathogenicity*
histoplasmosis / microbiology
histoplasmosis / pathology
lung diseases / microbiology
rodent diseases / microbiology
rodent diseases / pathology
siderophores / genetics
siderophores / metabolism*
spleen / microbiology
Access
Citation
ID:
267356
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
267356
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet