Aspergillus nidulans and chronic granulomatous disease: a unique host-pathogen interaction
Abstract
Invasive fungal infections are a major threat for patients suffering from chronic granulomatous disease (CGD), a primary immunodeficiency caused by a defect in the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase. Interestingly, Aspergillus (Emericella) nidulans is the second most encount …
Keywords
immunity
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
macrophages
neutrophils / immunology
innate
chronic / immunology
chronic / complications*
pmid:22829648
doi:10.1093/infdis/jis473
stefanie s v henriet
paul e verweij
adilia warris
aspergillosis / enzymology
aspergillosis / immunology
aspergillosis / microbiology*
aspergillus nidulans / physiology*
granulomatous disease
chronic / enzymology
host-pathogen interactions
alveolar / enzymology
alveolar / immunology
alveolar / microbiology
nadph oxidases / metabolism
neutrophils / microbiology
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267269
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