Leptin Suppresses Ghrelin-Induced Activation of Neuropeptide Y Neurons in the Arcuate Nucleus via Phosphatidylinositol 3-Kinase- and Phosphodiesterase 3-Mediated Pathway

Leptin Suppresses Ghrelin-Induced Activation of Neuropeptide Y Neurons in the Arcuate Nucleus via Phosphatidylinositol 3-Kinase- and Phosphodiesterase 3-Mediated Pathway

Kohno, Daisuke;Nakata, Masanori;Maekawa, Fumihiko;Fujiwara, Ken;Maejima, Yuko;Kuramochi, Motoki;Shimazaki, Takuya;Okano, Hideyuki;Onaka, Tatsushi;Yada, Toshihiko;
endocrinology 2007 Vol. 148 pp. 2251-2263
176
daisuke2007endocrinologyleptin

Abstract

Neuropeptide Y (NPY) neurons in the hypothalamic arcuate nucleus (ARC) play a central role in stimulation of feeding. They sense and integrate peripheral and ce

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