Eph signaling is required for segmentation and differentiation of the somites

Eph signaling is required for segmentation and differentiation of the somites

Lindsey Durbin, Caroline Brennan, Kensuke Shiomi, Julie Cooke, Arantza Barrios, Shantha Shanmugalingam, Brenda Guthrie, Rick Lindberg, Nigel Holder;Lindsey Durbin;Caroline Brennan;Kensuke Shiomi;Julie Cooke;Arantza Barrios;Shantha Shanmugalingam;Brenda Guthrie;Rick Lindberg;Nigel Holder;
genes & development 1998 Vol. 12 pp. 3096-
81
holder1998geneseph

Abstract

Somitogenesis involves the segmentation of the paraxial mesoderm into units along the anteroposterior axis. Here we show a role for Eph and ephrin signaling in the patterning of presomitic mesoderm and formation of the somites. Ephrin-A-L1 and ephrin-B2 ...

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