Efficacy of Liposomal Amphotericin B Combined with Gamma Interferon or Granulocyte-Macrophage Colony-Stimulating Factor for Treatment of Systemic Zygomycosis in Mice
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Efficacy of Liposomal Amphotericin B Combined with Gamma Interferon or Granulocyte-Macrophage Colony-Stimulating Factor for Treatment of Systemic Zygomycosis in Mice

M. Mar Rodríguez, Enrique Calvo, Marçal Mariné, F. Javier Pastor, Joan Fernandez-Ballart, Josep Guarro;M. Mar Rodríguez;Enrique Calvo;Marçal Mariné;F. Javier Pastor;Joan Fernandez-Ballart;Josep Guarro;
Antimicrobial agents and chemotherapy 2009 Vol. 53 pp. 3569-
125
guarro2009antimicrobialefficacy

Abstract

Granulocyte-macrophage colony-stimulating factor enhanced the efficacy of liposomal amphotericin B (LAMB) in a murine model of disseminated infection by Rhizopus oryzae, significantly prolonging survival and reducing tissue burden. The use of gamma interferon ...

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DOI:
10.1128/AAC.00456-09
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27156...

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