CBP-induced stimulation of c-Fos activity is abrogated by E1A
Abstract
The CBP protein stimulates transcription of cAMP-responsive genes by binding to the phosphorylated activation domain of the CREB transcription factor. Here we show that CBP stimulates transcription of Fos/Jun activity in F9 cells and that this response of mediated, at least partly, via c-Fos. We sho …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
amino acid sequence
Cultured
cell line
Nuclear Proteins / metabolism*
Transcription Factors / metabolism*
Molecular Sequence Data
transfection
transcription factors / genetics
tumor cells
transcriptional activation / physiology*
nuclear proteins / genetics
recombinant fusion proteins / metabolism
creb-binding protein
trans-activators*
pmid:7588605
pmc394573
a j bannister
t kouzarides
adenovirus e1a proteins / metabolism*
adenovirus e1a proteins / physiology
herpes simplex virus protein vmw65 / genetics
proto-oncogene proteins c-fos / genetics
proto-oncogene proteins c-fos / metabolism*
proto-oncogene proteins c-jun / genetics
proto-oncogene proteins c-jun / metabolism
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266603
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266603
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