Molecular structures and mechanisms of DNA break processing in mouse meiosis

Molecular structures and mechanisms of DNA break processing in mouse meiosis

Shintaro Yamada, Anjali Gupta Hinch, Hisashi Kamido, Yongwei Zhang, Winfried Edelmann, Scott Keeney;Shintaro Yamada;Anjali Gupta Hinch;Hisashi Kamido;Yongwei Zhang;Winfried Edelmann;Scott Keeney;
genes & development 2020 Vol. 34 pp. 806-
152
keeney2020genesmolecular

Abstract

Exonucleolytic resection, critical to repair double-strand breaks (DSBs) by recombination, is not well understood, particularly in mammalian meiosis. Here, we define structures of resected DSBs in mouse spermatocytes genome-wide at nucleotide resolution. ...

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ID: 266580
Ref Key: keeney2020genesmolecular
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