Functional interactions of peroxisome proliferator-activated receptor, retinoid-X receptor, and Sp1 in the transcriptional regulation of the acyl-coenzyme-A oxidase promoter
Abstract
Peroxisome proliferator-activated receptor (PPARs) are members of the nuclear receptor superfamily. For transcriptional activation of their target genes, PPARs heterodimerize with the retinoid-X receptor (RXR). The convergence of the PPAR and RXR signaling pathways has been shown to have an importan …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
Drosophila
gene expression regulation
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
cell line
Genes
Receptors
Cytoplasmic and Nuclear / metabolism*
Transcription Factors / metabolism*
Base Sequence
Molecular Sequence Data
Promoter Regions
nucleic acid
regulatory sequences
transfection
reporter
precipitin tests
mutagenesis
consensus sequence
retinoid x receptors
pmid:7776972
doi:10.1210/mend.9.2.7776972
g krey
a mahfoudi
w wahli
acyl-coa oxidase
enzymologic*
site-directed
oxidoreductases / genetics*
oxidoreductases / metabolism
retinoic acid / metabolism*
sp1 transcription factor / metabolism*
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266576
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