Aging and declining testosterone: past, present, and hopes for the future
Abstract
As men age, serum testosterone (T) levels decline, whereas serum luteinizing hormone (LH) levels increase somewhat or remain unchanged. Age-related reductions in T levels may be associated with alterations in body composition; energy level; muscle strength; physical, sexual, and cognitive functions; …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
adult
male
luteinizing hormone / blood
aged
middle aged
Rats
aging / physiology*
testosterone / blood*
pmid:22879528
pmc4077344
doi:10.2164/jandrol.112.017160
barry r zirkin
joyce lisa tenover
hormone replacement therapy
hypogonadism / drug therapy
leydig cells / drug effects
leydig cells / metabolism*
luteinizing hormone / physiology
inbred bn
testis / drug effects
testis / physiology*
testosterone / biosynthesis
testosterone / deficiency
testosterone / therapeutic use
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266551
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