Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model
Abstract
It is not known how biological changes in the lacrimal (LGs) and meibomian (MGs) glands contribute to dry eye disease (DED) in a time-dependent manner. In this study, we investigated time-sequenced changes in the inflammation, oxidative stress, and senescence of stem cells in both glands of an aging …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Inbred C57BL
animals
pubmed abstract
nih
national institutes of health
national library of medicine
male
Disease Models
Animal
Comparative Study
lacrimal apparatus / physiology
lacrimal apparatus / pathology*
oxidative stress
stem cells / pathology
lymph nodes / pathology
cellular senescence
aging / pathology*
jin suk ryu
pmid:32545199
pmc7313015
doi:10.3390/ijms21114169
chang ho yoon
mee kum kim
cornea / pathology
dacryocystitis / pathology
dry eye syndromes / pathology*
meibomian glands / pathology*
meibomian glands / physiology
stem cells / physiology
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266505
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