Mutations, mutation rates, and evolution at the hypervariable VNTR loci of Yersinia pestis
Abstract
VNTRs are able to discriminate among closely related isolates of recently emerged clonal pathogens, including Yersinia pestis the etiologic agent of plague, because of their great diversity. Diversity is driven largely by mutation but little is known about VNTR mutation rates, factors affecting muta …
Keywords
Evolution
databases
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
non-p.h.s.
N.I.H.
Extramural
DNA
Molecular*
Phylogeny
Genotype
disease outbreaks
gene dosage
dogs
plague / epidemiology
mutation*
plague / transmission
bacterial / genetics*
yersinia pestis / genetics*
pmid:17161849
doi:10.1016/j.mrfmmm.2006.11.007
amy j vogler
christine e keys
paul keim
genetic variation*
minisatellite repeats*
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266478
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