Adventures of the undead at kinetochores.
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Adventures of the undead at kinetochores.

Elowe, Sabine;
Molecular & cellular oncology 2021 Vol. 8 pp. 1876511
156
elowe2021adventuresmolecular

Abstract

At the metaphase-to-anaphase transition, phosphatase activity feeds back to reverse early mitotic phosphorylation events. Our recent work indicates that the pseudokinase domain of the spindle checkpoint protein BUB1 (Budding Uninhibited by Benzimidazoles 1) mitotic checkpoint serine/threonine kinase B (BUB1B, BUBR1) maintains kinase-phosphatase balance at the outer kinetochore during mitotic exit.

Keywords

mitosis kinetochore b56 bubr1 pp2a pseudokinase

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DOI:
10.1080/23723556.2021.1876511

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ID: 265453
Ref Key: elowe2021adventuresmolecular
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