Bifunctional Derivative of p,p'-Dichlorochalcone. Part II. Synthesis of a Novel Compound 2-[2-Carboxymethylthio-2-(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-4-thiazolidinone
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Bifunctional Derivative of p,p'-Dichlorochalcone. Part II. Synthesis of a Novel Compound 2-[2-Carboxymethylthio-2-(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-4-thiazolidinone

Dommisse, Roger;Groot, Alex De;Lemière, Guy;Ansari, Wajid Husain;Rahman, Mujeebur V.P.;Mukhtar, Sayeed;
molecules 1999 Vol. 4 pp. 232-237
133
dommisse1999bifunctionalmolecules

Abstract

The synthesis of 2-[2-carboxymethylthio-2-(4-chlorophenyl) ethyl]-2-(4-chlorophenyl) - 4-thiazolidinone (1) from p, p'- dichlorochalcone using thioglycollic acid in the presence of ammonium carbonate is described. Structural assignment and stereochemistry are discussed.

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chemistry Organic Chemistry Therapeutics. Pharmacology Science biochemistry

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