Visible Light-Promoted Cascade Radical Cyclization: Synthesis of 1,4-Diketones Containing Chroman-4-One Skeletons.

Visible Light-Promoted Cascade Radical Cyclization: Synthesis of 1,4-Diketones Containing Chroman-4-One Skeletons.

He, Xiang-Kui;Cai, Bao-Gui;Yang, Qing-Qing;Wang, Long;Xuan, Jun;
Chemistry, an Asian journal 2019
348
he2019visiblechemistry

Abstract

Visible light-induced cascade radical cyclization of aroyl chlorides with 2-(allyloxy)-benzaldehyde derivatives is developed. The method takes advantages of un-activated C=C bonds as the acyl radical acceptors and offers a mild and green approach for the synthesis of 1,4-diketons bearing biologically important chroman-4-one skeletons with moderate to good yields.

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ID: 26435
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26435
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10.1002/asia.201901078
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