Rational design of artificial dye-decolorizing peroxidases using myoglobin by engineering Tyr/Trp in the heme center

Rational design of artificial dye-decolorizing peroxidases using myoglobin by engineering Tyr/Trp in the heme center

Le-Le Li;Le-Le Li;Hong Yuan;Hong Yuan;Fei Liao;Fei Liao;Bo He;Bo He;Shu-Qin Gao;Shu-Qin Gao;Ge-Bo Wen;Ge-Bo Wen;Xiangshi Tan;Xiangshi Tan;Ying-Wu Lin;Ying-Wu Lin;
dalton transactions 2017 Vol. 46 pp. 11230-11238
209
li2017daltonrational

Abstract

The rational design of metalloenzymes provides advantages not only for illustrating the structure and function relationship of native enzymes, but also for creating functional artificial enzymes comparable to native enzymes. Dye-decolorizing peroxidases (DyPs) are a new family of heme peroxidases and have re

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