The number of patients with chronic kidney disease (CKD) in substitution therapy sessions dialysis program in Ukraine is growing. Improvement of methods of renal replacement therapy (RRT), chronic kidney disease, in particular, the use of modern dialysis technology has led to a significant increase in the life expectancy of patients. However, the mortality of the disease remains high. In its structure heavily reliant on cardiovascular disease, according to the National registry of patients with chronic kidney disease in 2011 it was 72 %. In this regard, there is actual determination of risk factors for these complications and the search for new methods to ensure their prevention. The author studied the effect of individually tailored and standard hemodialysis treatment programs on the risk factors of cardiovascular complications in patients with CKD. It is concluded that the custom-fitted options at the time of hemodialysis and ultrafiltration properties klirensovyh dialyzer electrolyte composition of the dialysate can achieve better results in the management of risk factors in patients with CKD.