n-acetyltransferase 2 slow acetylator genotype associated with adverse effects of sulfasalazine in the treatment of inflammatory bowel disease
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n-acetyltransferase 2 slow acetylator genotype associated with adverse effects of sulfasalazine in the treatment of inflammatory bowel disease

;Min Chen;Bing Xia;Bixiao Chen;Qiusha Guo;Jin Li;Mei Ye;Zhengguo Hu
indian journal of pharmacology 2007 Vol. 21 pp. 155-158
156
chen2007canadiann-acetyltransferase

Abstract

AIM: N-acetyltransferase 2 (NAT2) is an important enzyme catalyzing N-acetylation of sulfasalazine (SASP). The aim of the present study was to investigate associations of the genotypes of NAT2 with inflammatory bowel disease (IBD), and with adverse effects of SASP, which is used as the first-line treatment of IBD.

Keywords

Gastroenterology diseases of the digestive system

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DOI:
10.1155/2007/976804
URL:
http://dx.doi.org/10.1155/2007/976804

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ID: 256244
Ref Key: chen2007canadiann-acetyltransferase
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